News Page

Main Content

Joe Manganiello Shares Hospital Photos From 7-Year Health Battle, Says He Lost 60 Lbs After Surgery

Us Weekly's profile
Original Story by Us Weekly
October 15, 2026
Joe Manganiello Shares Hospital Photos From 7-Year Health Battle, Says He Lost 60 Lbs After Surgery

Context:

A seven-year health ordeal culminates in emergency intestinal surgery, during which the actor shed about 60 pounds and endured an ostomy, skin complications, and an undiagnosed autoimmune condition. He recounts the life‑saving decision by his then-wife Sofía Vergara and details a long recovery that stretched across years, foregrounding his resilience while his memoir Bloodlines gains attention. The story also threads through personal changes, including divorcing Vergara in 2024 and moving on with Caitlin O’Connor, to whom he proposed last year, while O’Connor promotes his new book. The narrative notes forthcoming releases in hardcover and audiobook formats and situates his health journey within a broader public spotlight. It signals ongoing questions about diagnosis, treatment, and the couple’s evolving support network as he looks ahead.

Dive Deeper:

  • Symptoms first appeared in 2016 after a collapse on a film set in North Carolina, leading to a life-threatening intestinal rupture and a major medical crisis.

  • Following a series of colonoscopies, he underwent emergency surgery to remove part of his intestines, a decision he attributes to a brutal but life-saving intervention by his wife at the time.

  • In the two weeks after surgery, he lost a total of 60 pounds, and imaging shows the ostomy bag top peeking above the sheets during recovery.

  • He describes developing multiple skin conditions during recovery, highlighting that his skin, an immune organ, was heavily affected across the seven years of illness.

  • The health battle is chronicled in his memoir Bloodlines, with patient details and a quote about Vergara’s role in his survival, underscoring the emotional toll of the experience.

  • Manganiello’s relationship with Vergara ended in separation in 2023 and divorce finalized in 2024; he moved on with Caitlin O’Connor, who announced his engagement last year.

  • O’Connor promoted Bloodlines and noted its hardcover and audiobook availability, framing the book’s release as a milestone during his ongoing health journey.

Latest Entertainment

Related Stories